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Dextromethorphan-Bupropion (Auvelity) for Depression: Clinical Trial Data for the New Rapid-Acting Antidepressant

Major depressive disorder (MDD) is a significant global health concern, affecting over 280 million people worldwide. While numerous pharmacological options exist, challenges remain in achieving timely, robust, and sustained antidepressant response. Dextromethorphan-bupropion is a novel oral antidepressant recently approved by the FDA for MDD in adults that may address some of these unmet needs. Key …

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Depressed vs. Anxious Brains: Differences in Brain Waves & Connectivity Revealed

Advanced analysis of multidimensional EEG data reveals significant differences in brain activity patterns between Generalized Anxiety Disorder (GAD) and Depressive Disorder (DD). The distinguishing factors seem to be differences in beta brain waves and functional connectivity between various brain regions. Key Facts: Patients with DD exhibited higher power spectrum density (PSD) values and fuzzy entropy …

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30+ New Antidepressants (2018): Drugs In Clinical Trials

Research suggests that upwards of 16 million American adults (6.7% of the adult population) are afflicted with major depressive disorder (MDD), a neuropsychiatric condition characterized by overwhelming sadness, behavioral changes, sleep disturbances, and cognitive deficits.  As of current, depression is the leading cause of disability in the United States among individuals between the ages of …

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Neurofeedback For Depression: An Effective Treatment?

Neurofeedback is a technique that involves training an individual to consciously alter the electrical activity (brain waves) within their brain.  The technique can be used as an intervention to improve symptoms of a variety of psychological conditions, including depression.  Individuals with depression tend to have abnormal brain wave activity compared to those without any preexisting …

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