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High Remnant Cholesterol Levels Linked to Depression Risk in U.S. Adults

Remnant cholesterol (RC), also known as triglyceride-rich lipoproteins, has been gaining increasing attention in recent years due to evidence linking it to cardiovascular disease, diabetes, chronic kidney disease, and other conditions. A new study suggests that elevated levels of remnant cholesterol in the blood may be associated with an increased risk of depression. Key Facts: …

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Adjunct Celecoxib for Depression & Mania: Treatment with a COX-2 Inhibitor

Celecoxib, a selective COX-2 inhibitor, shows promise as an effective and safe adjunct treatment for major depression and mania, according to a new comprehensive systematic review. The analysis also found celecoxib improved symptoms when used as a standalone antidepressant in patients with somatic disorders. However, evidence for efficacy in bipolar depression remains unclear. Key Facts: …

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Kybella (Deoxycholic Acid) Side Effects & Adverse Reactions (List)

Kybella (Deoxycholic acid) is an injectable medication engineered by Kythera Biopharmaceuticals and approved by the FDA in April 2015 for the management of moderate-to-severe submental fat (fat beneath the chin) in adults.  Reducing the appearance of a protruding “double chin” with Kybella entails visiting a medical professional to receive a series of subcutaneous [deoxycholic acid] …

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Whole-Body Hyperthermia For Depression: Turning Up The Heat To Enhance Mood?

Hyperthermia is defined as supraphysiological body temperature resulting from absorption and/or production of more heat than is dispelled.  Medically, local hyperthermia is often used as an adjunct to radiation and/or chemotherapy for the treatment of cancers.  It is thought that deliberate induction of hyperthermia to a cancerous region of the body increases the sensitivity of …

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Minocycline For Depression: Antibiotics As Antidepressants?

Minocycline is a broad-spectrum antibiotic of the tetracycline classification, indicating that its chemical structure consists of 4 hydrocarbon rings.  The fact that minocycline has a broad-spectrum mechanism indicates that it targets a wide-range of pathogenic (Gram-positive and Gram-negative) bacteria.  In fact, when compared to other tetracycline drugs, minocycline is regarded as having the “broadest spectrum” …

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