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Droperidol vs. Midazolam for Extreme Agitation in Dutch EDs

MHD featured image for droperidol, midazolam, and emergency sedation for extreme agitation.

A 2026 national survey of Dutch emergency physicians found wide variation in first-line medication choices for extreme agitation: without intravenous access, 34.7% preferred midazolam, 23.1% preferred droperidol, 14.3% preferred droperidol plus midazolam, and 10.4% preferred esketamine.1 The result is a practice map, not an outcome trial, but it shows how emergency clinicians are balancing rapid …

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ED Naloxone Need: 3.87M At-Risk Visits vs. 226K Overdoses

MHD featured image for emergency department naloxone distribution and opioid overdose prevention.

A 2026 emergency department claims analysis estimated 3.87 million United States ED visits in 2021 where take-home naloxone could have been clinically relevant, compared with 226,453 ED-treated opioid-overdose visits in the same database.1 The finding reframes naloxone distribution as an emergency-care workflow for overdose risk, polysubstance exposure, long-term opioid use, and patients who arrive after …

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Alcohol Use Disclosure in Tanzania: 10.6% Told Providers

A 2026 cross-sectional study in Moshi, Tanzania found that only 26 of 246 injury patients who drank alcohol, or 10.6%, had ever told a healthcare provider about their alcohol use.1 The calibration result was contrary to the prediction: measured alcohol stigma did not track disclosure, while alcohol-related consequences did. Research Highlights Disclosure was rare: among …

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