hit counter

Nighttime Caffeine Increased Impulsivity Through Dopamine in Fly Study

MHD featured image for nighttime caffeine, dopamine, and impulsive motor behavior.

A 2025 iScience study found that nighttime caffeine increased motor impulsivity in Drosophila, with dose-dependent loss-of-inhibition events across n = 30-32 flies per behavioral condition and stronger effects in female flies than male flies.1 The result does not prove that an evening coffee makes humans reckless, but it sharpens a neglected point: caffeine’s alertness benefit …

Read more

Parkinson’s Sex Differences: Male Flies Show Stronger Rotenone Stress

MHD featured image for Parkinson's sex differences and rotenone immune-gene response in Drosophila.

A 2026 Drosophila Parkinson’s model exposed male and female flies to 500 μM rotenone. By 60 days, male flies had worse survival/climbing than female flies; the paper is a vulnerability screen, not evidence that the same genes are ready human biomarkers.1 Research Highlights 500 μM rotenone split male and female flies: Iyer et al. used …

Read more