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Abnormal EEG Microstates Linked to Major Depression & Related Cognitive Impairment (2024 Study)

In the quest to understand the enigmatic nature of depression, scientists are turning to the intricate patterns of brain activity, seeking clues hidden within the electrical storm of thoughts and emotions. By examining electroencephalography (EEG) microstates—brief, recurring patterns of brain activity—researchers have begun to piece together how depression alters the fundamental dynamics of the brain. …

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Antidepressants & Iron Pathways: Targeting Ferroptosis to Treat Depression (2023 Review)

Depression, a debilitating mental disorder, stands as a significant challenge to global health, potentially becoming the leading cause of disability worldwide. Recent research has unearthed a promising connection between ferroptosis, a newly discovered form of cell death, and the onset of depression, offering fresh avenues for developing innovative antidepressant therapies. Traditional Chinese Medicine (TCM) and …

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tDCS of the DLPFC Treats Anhedonia in Depression & Improves Social Functioning (2024 Study)

In the quest to find more effective treatments for depression, particularly the challenging symptom of anhedonia, Transcranial Direct Current Stimulation (tDCS) emerges as a promising option. This non-invasive brain stimulation technique targets specific brain regions to modulate activity and potentially alleviate symptoms. A recent study has shed light on the efficacy and safety of targeting …

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Vegetarian Diets & Mental Health: Linked to Higher Psychological Distress Before Age 30 (2024 Study)

The link between vegetarianism and mental health has been a topic of much debate and speculation. Recent research from the 1970 British Cohort Study provides one of the most comprehensive analyses to date, exploring how vegetarianism at age 30 impacts psychological distress over time. This study’s findings challenge common misconceptions, revealing that vegetarianism is not …

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Gut Bacteria Composition in Major Depression vs. Healthy Controls & Antidepressant Treatment (2024 Study)

Depression, a multifaceted disorder characterized by pervasive sadness and lack of interest, extends beyond the brain to implicate the entire body, including the gut. Recent research has illuminated the significant role that gut microbiota plays in Major Depressive Disorder (MDD), suggesting a complex interplay between our microbial inhabitants and mental health. Highlights: Gut Microbiota & …

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Circadian Rhythm Disruption vs. Major Depression & Suicide Risk (2024 Study)

Circadian rhythms, the natural cycles of physiological and behavioral processes occurring within a 24-hour period, play a crucial role in our overall well-being. Recent research highlights the significant impact of these rhythms on the severity of major depressive disorder (MDD) and, crucially, on the intensity of suicidal ideation among those affected. A new study analyzed …

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Cytokine Profiles in Major Depression (Low IL-17C) & Comorbid Anxiety (2024 Study)

Recent studies have shed light on the intricate relationship between cytokines—proteins crucial for cell signaling in the immune system—depression, and anxiety. This exploration is pivotal in unveiling the potential biomarkers and therapeutic targets for major depressive disorder (MDD), particularly in patients experiencing their first episode and those untreated with drugs, with or without comorbid anxiety. …

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