Fibromyalgia Review: Exercise and CBT First, Medication Second
A 2026 narrative review says fibromyalgia is still diagnosed by symptoms, guidelines put exercise, education and CBT first, and approved drugs give modest relief.
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Published research on central sensitization.
Chemotherapy Neuropathy Links Pain and Chemobrain Mechanisms
A 2026 neuroscience review argues that chemotherapy-induced peripheral neurotoxicity should not be treated as a purely peripheral nerve problem: CIPN affects 70-90% of patients during chemot…
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Early-Life Visceral Stress Sensitized Auditory Brainstem Responses in Rats
A 40-rat early-life visceral stress study found auditory pathway sensitization without hearing-threshold loss: neonatal colorectal distension produced IBS-like visceral hypersensitivity, nor…
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Knee Osteoarthritis Pain and Fatigue Linked to Serum and CSF Metabolites
A 2026 targeted metabolomics study of knee osteoarthritis found 33 altered serum metabolites and 10 altered cerebrospinal-fluid metabolites, but the symptom signal split by compartment: seru…
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Pregabalin for CRPS: 3 Adult Cases Had VAS Pain Drops
A 2026 Taiwanese case series reported VAS pain drops in all 3 adults treated with pregabalin for type I complex regional pain syndrome: 9 to 5, 2 to 1, and 6 to 3 after doses of 75-150 mg/da…
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