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Olanzapine for Anorexia: A Promising Treatment Both Systemically & Intranasally (2023 Study)

Anorexia nervosa (AN), a severe mental disorder characterized by an intense fear of gaining weight and a distorted body image, remains a formidable challenge in psychiatric treatment. Recent research has shone a light on the potential of olanzapine, an atypical antipsychotic, in offering new hope through both systemic and innovative intranasal administration methods in animal …

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Vraylar (Cariprazine) & Weight Gain vs. Loss: What You Should Know

Vraylar (Cariprazine), also sold under the name Reagila [in European countries], is an atypical antipsychotic developed by the pharmaceutical company Allergan.  In 2015, Vraylar received FDA approval for the treatment of schizophrenia and mania associated with bipolar disorder.  From a pharmacodynamic perspective, Vraylar functions predominantly as a partial agonist at D3 and D2 dopamine receptors, …

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Drinking Coffee & Weight Loss? What You Should Know

Coffee is a brewed drink prepared from the roasting of coffee beans, which technically, are seeds of berries produced by the Coffea plant.  Specifically, when Coffea plant berries ripen, they are picked, processed, dried, roasted, ground, brewed with boiling water, and served as the beverage we’ve come to know as coffee.  Although the Coffea plant …

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Naltrexone & Weight Loss: What Should You Expect?

Naltrexone is a chemical initially synthesized in 1963 and patented thereafter by the pharmaceutical company Endo Laboratories in 1967.  It is considered a substituted derivative of oxymorphone in that the tertiary amine methyl-constituent is replaced with an allyl group (specifically an N-cyclopropylmethyl group) – or a longer chain of carbon atoms.  It was initially approved …

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Amitriptyline & Weight Gain: The Reason 50% Discontinue Treatment

Amitriptyline (Elavil) is the most popular TCA (tricyclic antidepressant) medication on the market. It is primarily utilized for the treatment of depression, and in other cases, migraine headaches and anxiety disorders. The drug functions primarily by inhibiting the reuptake of the serotonin transporter, which increases extracellular levels of the neurotransmitter serotonin. Although serotonin is primarily …

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Lyrica & Weight Gain: What Should You Expect?

Lyrica (Pregabalin) is a drug that is approved for the treatment of neuropathic pain as well as partial seizures in adults. In some countries (outside the United States) it has also been successfully used for the treatment of anxiety disorders. Lyrica is often preferred over opioid medications in the treatment of chronic pain as well …

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