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Antidepressants, Bacterial Mutations, & Antibiotic Resistance?

Antibiotics have long been the cornerstone of modern medicine, but their effectiveness is increasingly threatened by the rise of antibiotic resistance. While the overuse of antibiotics is a well-acknowledged culprit, recent research reveals a surprising and relatively unexplored contributor: antidepressants. Highlights: Antidepressants and Resistance: Antidepressants, particularly those used in large quantities like SSRIs and SNRIs, …

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Best Antidepressants for Preventing Depression Relapse & Maintenance Treatment (Study)

Depression is a complex, often long-term condition requiring careful management. Recent research has shed light on the effectiveness of various antidepressants during the maintenance phase of major depressive disorder (MDD). Highlights: Extensive Study: The meta-analysis included 34 double-blind, placebo-controlled trials with a total of 9,384 participants. Multiple Drugs Analyzed: 20 different antidepressants were compared for …

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Antidepressants May Trigger Mania In Bipolar Disorder via Mitochondria

Antidepressants, commonly used to treat major depressive episodes in bipolar disorder, might have more profound effects on our body’s energy factories, the mitochondria, than previously understood. A recent study examined how certain antidepressants alter mitochondrial energetics, potentially influencing the risk of treatment-emergent mania in bipolar disorder patients. Highlights: Antidepressants Double Edged Sword: While crucial for …

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Analyzing Cardiovascular Effects & Risks of Newer Antidepressants

Depression is a prevalent and serious condition in older adults and those with cardiovascular disease. Serotonin reuptake inhibitors (SSRIs) are commonly used to treat depression, but when they’re ineffective, alternative antidepressants must be considered. Key Facts: Depression in Older Adults and Cardiovascular Patients: Affects 15-20% of patients with coronary heart disease. Limitations of SSRIs: While …

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Long-Term Antidepressant (SSRI) Use Increasing: Overprescription & Withdrawal Hesitancy

The rise in antidepressant prescribing, especially selective serotonin reuptake inhibitors (SSRIs) since the 1980s, is a complex phenomenon with broad implications for public health. While these medications are crucial for many, the increase in long-term use has raised concerns about overprescription, side effects, and withdrawal challenges. Key Facts: Rising Prescriptions: Antidepressant prescriptions, particularly SSRIs, have …

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Top 12 Antidepressant Nutrients & Foods for Depression Treatment

Depression is a growing public health concern, but nutrition may offer a pathway for prevention and treatment. A new research study identified the most nutrient-dense foods for brain health to inform dietary recommendations. Key Facts: 12 nutrients have evidence supporting a role in preventing and treating depression, including omega-3s, B vitamins, minerals like magnesium, and …

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30+ New Antidepressants (2018): Drugs In Clinical Trials

Research suggests that upwards of 16 million American adults (6.7% of the adult population) are afflicted with major depressive disorder (MDD), a neuropsychiatric condition characterized by overwhelming sadness, behavioral changes, sleep disturbances, and cognitive deficits.  As of current, depression is the leading cause of disability in the United States among individuals between the ages of …

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