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Vraylar (Cariprazine) Approved For Schizophrenia & Bipolar Disorder

Vraylar (Cariprazine) was approved by the FDA on September 17, 2015 for the treatment of schizophrenia and mania associated with bipolar disorder.  In clinical trials, the drug was referenced as “RGH-188” – containing Cariprazine as the primary active ingredient.  The drug had completed Phase III clinical trials in 2012, and was pending FDA approval for …

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6 New Autism Medications (2015): Drugs In Clinical Trials

Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder that significantly affects behavior, cognitive function, and social skills.  Those with the disorder often engage in repetitive behaviors, suffer from low intelligence, and have severe difficulty verbalizing their thoughts.  In fact, a subset individuals with autism are incapable of any verbal communication and resort to gesturing …

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3 New Narcolepsy Medications (2015) In Clinical Trials

Narcolepsy is a neurological disorder associated with the brain’s inability to regulate sleep-wake cycles (and the circadian rhythm).  As a result, individuals diagnosed with narcolepsy often experience excessive daytime sleepiness and may fall asleep unexpectedly.  Some have suggested that the excessive daytime sleepiness stemming from narcolepsy is akin to how a normal person feels if …

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3 New Bipolar Medications (2015): Drugs In Clinical Trials

Bipolar disorder is a condition characterized by cyclical mood swings, transitioning from depression to mania (or hypomania).  For a period of time, an individual with bipolar disorder will experience debilitating bouts of depression – and often unexpectedly, their entire neurophysiology will shift to facilitate a state of mania (elevated mood).  Diagnostically, there are multiple types …

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20 New Antidepressants In The Pipeline (2015): Drugs In Clinical Trials

For individuals in the United States between the age of 15 and 44, major depression is the leading cause of disability.  Major depression is often a heritable condition, caused by maladaptive genes getting transferred across generations.  That said, not everyone diagnosed with major depressive disorder inherited the condition from ancestors or should be blaming their …

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20+ New Schizophrenia Medications In Development (2015)

It is estimated that over 2.5 million adults in the United States have been diagnosed with schizophrenia; this equates to approximately 1.1% of the population.  There are many different types of schizophrenia, in fact, genetic clusters suggest it is 8 distinct diseases.  Therefore not everyone diagnosed with schizophrenia has the same set of symptoms. Certain …

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5 New Anxiety Medications In Development (2015)

There are currently many different types of medications that can be utilized to treat anxiety (list of anxiolytics). The problem is that many of the drugs are poorly tolerated and/or produce significant unwanted side effects. Perhaps the most effective class of drugs to treat anxiety are the benzodiazepines as they provide rapid and significant relief. …

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