A 2026 real-world study involving 1,174 children with epilepsy proposed a levetiracetam therapeutic drug monitoring range of 2.82-24.37 mcg/mL, much lower than commonly cited adult-style ranges, but the same data also warned against treating a drug level as a stand-alone seizure-control predictor. Research Highlights Lower pediatric range: Sun et al. proposed an observational levetiracetam range …
A 2026 structured review of autoimmune drug-resistant focal epilepsy argues for a narrow but clinically important claim: immune mechanisms can make seizures refractory in selected patients, but the evidence supports targeted testing and immunotherapy triage rather than treating every medication-resistant seizure disorder as autoimmune. Research Highlights Autoimmune epilepsy is a subset: Kunecki et al. estimated …
A 2026 study involving 118 prostate cancer survivors found the clearest lifestyle-cognition signal around smoking: smokers learned fewer words across repeated verbal-memory trials, while obesity and physical activity produced narrower reaction-time findings and no significant anxiety or depression differences. Research Highlights Smoking tracked verbal learning: in 118 prostate cancer survivors, smokers scored lower on Verbal …
A 2026 systematic review of advanced neuroimaging in multiple sclerosis narrowed 600 database records to 12 studies and found the clearest cognition signal in basal ganglia iron-sensitive MRI measures, while thalamic susceptibility was more variable and often tangled with atrophy. Research Highlights Basal ganglia signal was strongest: across 12 studies, elevated susceptibility or iron-related metrics …
A 2026 Australian co-design study found that 70 of 73 surveyed health professionals, plus all 5 people with lived experience and all 6 carers interviewed, described outpatient care after eating-disorder hospital discharge as inadequate. Research Highlights Outpatient care was the main gap: 70 of 73 surveyed health professionals and all 11 interviewed patients/carers said care …
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling multisystem illness marked by post-exertional malaise, cognitive dysfunction, pain, sleep disruption, and autonomic symptoms; a 2026 PLOS One qualitative analysis of 505 memorial entries found that bereaved accounts repeatedly placed death inside 4 overlapping contexts: systemic neglect, clinical dismissal, social disconnection, and personal functional collapse.1 Research Highlights …
A 2026 Acta Neuropathologica study found that oligomeric tau was linked to early nuclear lamina disruption in Alzheimer’s disease tissue, PS19 tauopathy mice, and human induced pluripotent stem cell (iPSC)-derived neurons.1 The strongest claim is mechanistic: tau oligomers appeared to deform the nuclear envelope and disturb chromatin before overt neurodegeneration, but the work does not …