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Losartan, Especially as Nanoparticles, Eased Cerebellum Damage in Rats

MHD card showing a glowing emerald cerebellum with a tree-like inner branching pattern dotted with amber nanoparticle spheres and a faint rat silhouette, illustrating a rat study in which losartan eased toxin damage to the cerebellum.

In rats with toxin-damaged cerebellums, 4 weeks of the blood-pressure drug losartan reduced oxidative damage, inflammation and tissue injury. A nanoparticle version did better on several tissue and staining measures, but not on gene activity.1 Research Highlights A small rat experiment: 24 male rats in 4 groups of 6. Three groups received carbon tetrachloride (a …

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Socioeconomic Data Nudged Up EEG ADHD Screening Accuracy

MHD card showing a glowing cyan EEG electrode cap with brainwave traces flowing down into amber house, graduation-cap and food-bowl icons, illustrating a study in which adding socioeconomic data slightly raised EEG-based ADHD screening accuracy.

Adding socioeconomic background to EEG brain recordings slightly improved how well a deep-learning model sorted 127 US university students by ADHD screening status. Accuracy rose on all 4 brain-recording tasks, but the gain was not statistically significant on any of them.1 Research Highlights About 9 in 10 classified correctly from EEG alone: tested on students …

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Subthreshold Depression Linked to Inflammation and Altered Brain Connectivity

MHD card showing a side-view brain with a glowing crimson cingulate arc and a blood vessel releasing small red particles, illustrating a study in which university students with subthreshold depression had altered brain connectivity and slightly higher inflammatory proteins.

University students with subthreshold depression, meaning real depressive symptoms that fall short of a major depression diagnosis, had stronger connections in 3 cingulate brain circuits and slightly higher levels of 3 inflammatory proteins than healthy students, according to a 2026 brain-imaging study from China.1 Research Highlights Stronger cingulate connections: resting brain scans of 126 students …

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Guanfacine Eases Hyperactivity in Autism; Inflammation Theory Untested

MHD card showing a teal prefrontal dendrite with a magnified membrane of closed HCN channels and an amber microglia cell inside a dashed outline, illustrating that guanfacine eased hyperactivity in autistic children while its anti-inflammatory role remains untested.

Guanfacine, a non-stimulant ADHD medication, reduced hyperactivity in autistic children in a placebo-controlled trial. A 2026 review argues it may also steady prefrontal brain signaling and calm the brain’s immune cells, but that immune effect has never been tested with guanfacine itself.1 Research Highlights Hyperactivity fell in the largest autism trial: in 62 autistic children, …

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