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Drugs

How Long Does Prednisone Stay In Your System After Stopping?

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Prednisone is a common synthetic corticosteroid medication that was initially synthesized in 1955.  Upon ingestion of prednisone, it doesn’t elicit significant biological effects until converted via the liver to the pharmacologically active chemical “prednisolone.”  Prednisolone functions as an irreversible glucorticoid receptor agonist, binding to alpha glucorticoid receptors (AlphaGRs) and beta glucorticoid receptors (BetaGRs) within bodily tissues …

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How Long Does Ambien Stay In Your System?

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Ambien (Zolpidem) is a popular medication prescribed for the treatment of insomnia.  It is classified as a “nonbenzodiazepine” due to the fact that it shares a similar mechanism of action with benzodiazepines, but differs in its chemical structure.  Ambien delivers its sedative, hypnotic (sleep-inducing) effects by modulating receptors of GABA (gamma-amino-butyric-acid). It specifically functions primarily …

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How Long Does Suboxone Stay In Your System?

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Suboxone is a semisynthetic drug manufactured by Reckitt Benckiser pharmaceuticals for the treatment of opioid dependence.  It was introduced to the market in October 2002 and gained popularity as a result of its efficacy and reduced potential for abuse compared to other opioid replacement agents such as methadone.  The drug is comprised of the ingredients …

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How Long Does Vyvanse Stay In Your System?

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Vyvanse (Lisdexamfetamine) is a psychostimulant medication manufactured by Shire Pharmaceuticals for the treatment of ADHD (attention-deficit/hyperactivity disorder).  Many consider Vyvanse to be a “new and improved” successor of the drug Adderall.  Vyvanse contains the ingredient Lisdexamfetamine which is pharmacologically inactive until metabolized; hence being classified as a “prodrug.” The fact that Vyvanse is a prodrug …

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How Long Does Effexor Stay In Your System After Stopping It?

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Effexor (Venlafaxine) is a SNRI (serotonin-norepinephrine reuptake inhibitor) medication prescribed primarily for the treatment of major depressive disorder.  It was initially introduced to the market by Wyeth in 1993 when it became the first dual-reuptake inhibitor to attain FDA approval for depression.  It differed from the SSRIs in that in addition to solely inhibiting reuptake …

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How Long Does Zoloft Stay In Your System After Stopping?

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Zoloft (Sertraline) is a popular SSRI (selective-serotonin reuptake inhibitor) prescribed primarily for the treatment of major depressive disorder.  It is also utilized medically for the treatment of obsessive-compulsive disorder (OCD), panic disorder, PTSD, and social phobia.  The drug has been available as a prescription antidepressant since 1991 when it was introduced by Pfizer. Though a …

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