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Vraylar (Cariprazine) & Weight Gain vs. Loss: What You Should Know

Vraylar (Cariprazine), also sold under the name Reagila [in European countries], is an atypical antipsychotic developed by the pharmaceutical company Allergan.  In 2015, Vraylar received FDA approval for the treatment of schizophrenia and mania associated with bipolar disorder.  From a pharmacodynamic perspective, Vraylar functions predominantly as a partial agonist at D3 and D2 dopamine receptors, …

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Bunavail Withdrawal Symptoms: List of Possibilities

Bunavail is a bucally-formatted medication comprised of buprenorphine and naloxone that was approved by the FDA in 2017 for the treatment of opioid dependence.  The buprenorphine component of Bunavail functions as a partial mu-opioid receptor agonist whereby it stimulates mu-opioid receptors in the brain to prevent opioid cravings and/or attenuate harsh withdrawal symptoms upon cessation …

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9 New Anxiety Medications (2018): Drugs In Clinical Trials

Collected data from the Anxiety and Depression Association of America (ADAA) suggests that upwards of 40 million adults are affected by anxiety, or approximately 18% of the United States population.  Among the 40 million adults who are affected by anxiety, it is estimated that approximately: 19 million suffer from specific phobias; 15 million suffer from …

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30+ New Antidepressants (2018): Drugs In Clinical Trials

Research suggests that upwards of 16 million American adults (6.7% of the adult population) are afflicted with major depressive disorder (MDD), a neuropsychiatric condition characterized by overwhelming sadness, behavioral changes, sleep disturbances, and cognitive deficits.  As of current, depression is the leading cause of disability in the United States among individuals between the ages of …

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Cannabidiol (CBD) Side Effects & Adverse Reactions

CBD (Cannabidiol) is a phytocannabinoid with medicinal properties derived from the cannabis plant (i.e. marijuana).  Of all ~113 active phytocannabinoids, or plant-based chemical constituents within the cannabis plant, cannabidiol is most abundant and accounts for approximately 40% of the plant’s extract.  Unlike other phytocannabinoids that induce intoxicating effects (e.g. THC or tetrahydrocannabinol), cannabidiol is devoid …

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Zoloft (Sertraline) & Headaches: Does It Cause or Treat Headaches?

Zoloft (Sertraline), is an SSRI (selective serotonin reuptake inhibitor) prescribed for the treatment of major depressive disorder, OCD (obsessive-compulsive disorder), panic disorder, and social anxiety disorder.  It was approved by the FDA in 1991 and initially marketed by the pharmaceutical company Pfizer.  In 2013, Zoloft became the single most popular antidepressant medication in the United …

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Humira (Adalimumab) & Weight Gain: A Common Reaction

Humira (Adalimumab) is a biologic, immunosuppressant medication sold and marketed by the pharmaceutical company AbbVie Inc.  More specifically, Humira functions as a TNF inhibitor whereby it binds to and blocks the physiologic effect of the proinflammatory cytokine known as “TNF-alpha.”  Blockade of inflammation induced by TNF-alpha makes Humira useful for the treatment of many autoimmune …

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