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Transcranial Magnetic Stimulation (TMS) For Depression: An Effective Treatment?

According to the World Health Organization (WHO), depression is projected to become the number one global disease burden by 2030.  Present-day statistics suggest that depression affects over 350 million people worldwide.  Among those who are depressed, seeking professional psychiatric treatment is often helpful. An estimated 66% of all individuals who seek treatment are able to …

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Nanotechnology For Depression: The Futuristic Potential of Nanopsychiatry

Most pharmacological-based treatments for depression aim to increase levels of various neurotransmitters, particularly serotonin (5-HT).  It is thought that approximately 2 out of 3 individuals that seek treatment with standard antidepressants such as SSRIs and SNRIs are able to attain therapeutic relief.  For a certain percentage of these individuals, the benefits of using pharmaceutical interventions …

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Gene Therapy For Depression: A Futuristic Treatment

Despite the fact that pharmaceutical companies continue to promote the concept of “chemical imbalances” as the root cause of depression, this is a vast oversimplification of an infinitely more complex condition.  While a chemical imbalance may be one of the primary contributing factors to a person’s depression, what causes the chemicals (neurotransmitters) to become imbalanced …

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RNAi For Depression: siRNA Targets SERT & 5-HT1A for Antidepressant Effect

It seems as though society is on the verge of ushering in a new generation of treatment modalities for depression and other psychiatric conditions.  While most people turn to pharmaceutical drugs for major depressive disorder, approximately 1 out of 3 people fail to get sufficient symptomatic relief.  To make matters worse, many end up trying …

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Genetically Modified Mice: PDE4B Inhibition Increases Intelligence, Reduces Anxiety

Perhaps you’ve heard of the fictional story “Flowers for Algernon” about a laboratory mouse named Algernon.  The mouse undergoes a nootropic-esque surgical procedure that dramatically amplifies his intelligence.  The experiment is deemed so successful, that scientists decide to test the procedure in a human character named Charlie Gordon. Prior to the artificial enhancement of Charlie’s …

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