Treatment with commonly prescribed antidepressants may cause a small proportion of patients to develop persistent sexual side effects that continue even after stopping the medication. This condition is known as post-SSRI sexual dysfunction (PSSD). Key Facts: The study found 0.46% of patients developed erectile dysfunction that continued after stopping antidepressants. This suggests the risk of …
Celecoxib, a selective COX-2 inhibitor, shows promise as an effective and safe adjunct treatment for major depression and mania, according to a new comprehensive systematic review. The analysis also found celecoxib improved symptoms when used as a standalone antidepressant in patients with somatic disorders. However, evidence for efficacy in bipolar depression remains unclear. Key Facts: …
Lexapro (escitalopram) and Prozac (fluoxetine) are two medications within the selective-serotonin reuptake inhibitors (SSRI) classification that are commonly administered for the treatment of neuropsychiatric disorders. The development of Lexapro (escitalopram) was initiated in 1997 by Lundbeck and Forest Laboratories – whereas the development of Prozac (fluoxetine) was initiated in the 1970s by chemists (Bryan Molloy …
Celexa (citalopram) and Lexapro (escitalopram) are chemically-analogous medications within the selective-serotonin reuptake inhibitor (SSRI) classification that are regularly prescribed for the management of neuropsychiatric disorders. Chemically, Celexa contains enantiomers S-citalopram and R-citalopram – whereas Lexapro solely contains S-citalopram (hence its chemical name “es-citalopram”). The chemical “citalopram” (Celexa) was originally synthesized in 1972 by scientists at …
Lexapro (escitalopram) and Zoloft (sertraline) are medications of the selective-serotonin reuptake inhibitor (SSRI) classification utilized most commonly for the management of major depressive disorder (MDD). Lexapro was co-developed by the pharmaceutical companies Lundbeck and Forest Laboratories (starting in 1997) and received U.S. FDA approval for medical use in 2002. Zoloft was developed by the pharmaceutical …
Prozac and Zoloft are two common SSRI medications prescribed for the treatment of neuropsychiatric conditions, most notably, major depressive disorder (MDD). Prozac was developed by the pharmaceutical company Eli Lilly and went on to receive initial FDA approval in December 1987 as an antidepressant. Comparatively, Zoloft was developed by the pharmaceutical company Pfizer and went …
Fetzima (Levomilnacipran) is a medication prescribed for the treatment of major depressive disorder in adults. Although it is similar to the drug Savella (Milnacipran), Fetzima exhibits unique pharmacodynamics in that it functions as a serotonin-norepinephrine reuptake inhibitor (SNRI) with a 2-fold affinity for norepinephrine reuptake inhibition – relative to serotonin reuptake inhibition. In other words, …