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Adderall Tolerance: Causes & How To Prevent It

Nearly all individuals taking Adderall can attest to the fact that its psychostimulatory effect is most potent after an initial “first-time” dosage.  Thereafter, its efficacy is generally maintained for weeks, or perhaps months after the initial dosage with favorable results.  However, eventually Adderall users may notice that its therapeutic psychostimulation seems to have dwindled and/or …

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How Long Does Vyvanse Stay In Your System?

Vyvanse (Lisdexamfetamine) is a psychostimulant medication manufactured by Shire Pharmaceuticals for the treatment of ADHD (attention-deficit/hyperactivity disorder).  Many consider Vyvanse to be a “new and improved” successor of the drug Adderall.  Vyvanse contains the ingredient Lisdexamfetamine which is pharmacologically inactive until metabolized; hence being classified as a “prodrug.” The fact that Vyvanse is a prodrug …

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How Long Does Ritalin Stay In Your System?

Ritalin is a psychostimulant drug used medically for the treatment of attention-deficit/hyperactivity disorder (ADHD) and narcolepsy.  It contains the active ingredient methylphenidate, which functions as a catecholamine reuptake inhibitor, primarily of dopamine (DAT) and norepinephrine (NET) transporters.  This reuptake inhibition (NDRI) facilitates increases in extracellular dopamine and norepinephrine concentrations, thereby substantially enhancing neurophysiological arousal. Upon …

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14 New ADHD Medications In the Pipeline (2015)

ADHD (attention-deficit/hyperactivity disorder) is a condition characterized by inability to concentrate and often comorbid hyperactive behaviors.  It is considered the most common psychiatric disorder among children and adolescents (affecting approximately 5%) and is fairly common among adults (affecting approximately 4%).  Individuals with ADHD may face serious difficulties completing projects, studying at school, holding a steady …

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Neurofeedback For ADHD: Is It An Effective Treatment?

Neurofeedback is a practice devised to optimize the electrical activity within a person’s brain a.k.a. adjust their brain waves.  It is based on the premise that abnormal electrical activity in certain regions of the brain may contribute to various psychological conditions and may compromise mental performance.  The goal of neurofeedback is to correct electrical abnormalities …

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Guanfacine For ADHD: An Effective Treatment & Adjunct

Guanfacine is a drug that was developed primarily for the treatment of hypertension (high blood pressure).  It has been proven as an effective medication to reduce both systolic and diastolic blood pressure via its effect on Alpha-2 adrenergic autoreceptors.  It functions by stimulating these receptors (as an agonist) and reducing activation of the sympathetic nervous …

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Clonidine For ADHD: An Effective Treatment & Adjunct

Clonidine is a drug that is commonly prescribed to treat high blood pressure.  Clonidine is also commonly used as a treatment for anxiety and as an intervention to minimize drug withdrawal symptoms.  On occasion, it is prescribed off-label for the treatment of PTSD, borderline personality disorder, stress, and insomnia. It functions primarily as an Alpha-2 …

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