Mental Health DailyResearch. Evidence. Perspective.Published research on synaptic plasticity.
A 2026 Generation Scotland study linked traumatic physical injury to diagnosis-stratified blood methylation differences in 4,308 people.1 The clearest recurrent-depression signal pointed tow…
Read articlePTSD and major depressive disorder co-occur in roughly half of patients with either diagnosis, and the comorbid presentation is more severe than either alone. The mechanistic question has be…
Read articleGW043 emerges as a promising new compound in the treatment of depression showcasing rapid and significant antidepressant effects by targeting NMDA receptors (NMDARs). This mechanism offers h…
Read articleIn the complex and evolving field of neuroscience, the role of synaptic plasticity in psychiatric disorders has garnered significant attention. d-Cycloserine (DCS), a partial agonist of the …
Read articleResearchers have uncovered a critical role for the metabolic enzyme acetyl-CoA synthetase short-chain family member 2 (ACSS2) in depression, identifying it as a novel target for rapid-acting…
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