Ketamine and its S-enantiomer esketamine (sold as Spravato) are now established treatments for treatment-resistant depression and acute suicidality. The standard safety pitch from sponsors and clinics: at single sub-anesthetic doses, in supervised settings, addiction risk is minimal. A new case report in BJPsych Open documents a patient for whom that pitch failed catastrophically — and …
Major Depressive Disorder (MDD) is not just a mental health concern; it’s a complex interplay of psychological, environmental, and biological factors, where the most tragic outcome can be suicide. Recent research has unveiled a potential link between the immune system’s inflammatory response and the increased risk of suicide among those suffering from MDD. By examining …
Suicide, a tragic end to around 800,000 lives each year, remains one of the most perplexing and devastating phenomena in mental health. Despite the vast number of studies and data, accurately predicting who is at risk of suicide has remained largely elusive, with current tools heavily reliant on subjective assessments and the clinician’s experience. A …