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Evening Chronotype & Lower Efficacy of SSRI Antidepressants (2024 Study)

Recent research in the Australian Genetics of Depression Study reveals a fascinating connection between an individual’s chronotype and the efficacy of antidepressants. A study, focusing on selective-serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), suggests that evening chronotypes may experience poorer responses to these medications. Highlights: Chronotype Impact: Individuals with an evening chronotype reported …

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Unspecified Anxiety Disorder: Expert Treatment Recommendations in Japan (2023)

Anxiety disorders, a widespread mental health concern, encompass a range of conditions, each with specific characteristics and treatment protocols. However, the realm of “unspecified anxiety disorder” remains a grey area, often challenging healthcare professionals due to its lack of clear-cut guidelines. A recent study aimed to fill this gap by developing a consensus among experts …

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Lexapro (Escitalopram) vs Zoloft (Sertraline): Extensive Comparison

Lexapro (escitalopram) and Zoloft (sertraline) are medications of the selective-serotonin reuptake inhibitor (SSRI) classification utilized most commonly for the management of major depressive disorder (MDD).  Lexapro was co-developed by the pharmaceutical companies Lundbeck and Forest Laboratories (starting in 1997) and received U.S. FDA approval for medical use in 2002. Zoloft was developed by the pharmaceutical …

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How Long Does It Take For Zoloft To Work or “Kick In”?

Zoloft (Sertraline) is a selective-serotonin reuptake inhibitor (SSRI) prescribed for a variety of medical conditions, including: major depressive disorder, obsessive-compulsive disorder, panic disorder, and social anxiety disorder.  On occasion, Zoloft is even used off-label to help manage symptoms of premenstrual syndrome (PMS), body dysmorphic disorder, vascular headaches, and premature ejaculation. Though the effectiveness of Zoloft …

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Intermittent Explosive Disorder (IED): Causes, Symptoms, Treatment

Intermittent explosive disorder (IED) is regarded as a subtype of impulse control disorder characterized by impulsive, uncontrollable explosive outbursts of anger, aggression, and/or rage – sometimes accompanied by violence.  To be considered intermittent explosive disorder, the explosive outbursts of anger must be triggered in situations and/or conditions in which such anger is unjustified.  In other …

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