In the digital age, Internet Addiction Disorder (IAD) emerges as a complex interplay of technology, psychology, and genetics. This intricate relationship underscores the need for a multidisciplinary approach to understanding and addressing IAD. A recent study analyzed the genetic underpinnings of internet addiction and discovered a strong link with the serotonin 2A receptor gene (HTR2A) …
Major Depressive Disorder (MDD) impacts millions globally, making it a significant public health challenge. Traditional treatments like Selective Serotonin Reuptake Inhibitors (SSRIs) don’t work for everyone, highlighting the need for innovative approaches. Recent clinical trials exploring the use of empagliflozin, a medication originally used to lower blood sugar in diabetes patients, have shown promising results …
Suicide, a tragic end to around 800,000 lives each year, remains one of the most perplexing and devastating phenomena in mental health. Despite the vast number of studies and data, accurately predicting who is at risk of suicide has remained largely elusive, with current tools heavily reliant on subjective assessments and the clinician’s experience. A …
Quetiapine, a second-generation antipsychotic medication, is renowned for its efficacy in managing a spectrum of psychiatric conditions, including schizophrenia, bipolar disorder, and major depressive disorder (MDD). Despite its broad therapeutic utility and a generally favorable side effect profile, quetiapine’s role in rare instances of inducing psychotic symptoms warrants a closer examination. Highlights: Quetiapine’s Mechanism of …
Depression, a pervasive global health issue, significantly impairs quality of life and burdens the healthcare system. Despite the availability of numerous antidepressants, their effectiveness is often limited, pushing researchers to explore alternative treatments. Berberine, a natural compound with a diverse pharmacological profile, has shown promising antidepressant effects, offering a potential complementary or alternative approach to …
Major Depressive Disorder (MDD) significantly alters the brain’s network connectivity, with disturbances in the default mode network (DMN), salience network (SN), and dorsal attention network (DAN). A new study reveals how escitalopram, a common antidepressant, can partially reverse these abnormalities, offering insights into the biological underpinnings of its therapeutic effects. This research deepens our understanding …
Suicide remains a leading cause of death worldwide, with its prevention a top priority for both public health initiatives and individual care strategies. Recent research in the US Army offers new insights into the genetic underpinnings of suicide attempts, suggesting that polygenic risk scores (PRS) could become a valuable tool in identifying individuals at risk. …