Mental Health DailyResearch. Evidence. Perspective.Published research on oxidative stress.
In 144 Finnish adults, smell loss rose from healthy aging to MCI to Alzheimer's, and nasal smell-tissue cells from MCI and Alzheimer's donors showed lower NRF2 antioxidant gene activity in a…
Read articleIn rats with toxin-damaged cerebellums, 4 weeks of the blood-pressure drug losartan reduced oxidative damage, inflammation and tissue injury. A nanoparticle version did better on several tis…
Read articleA 2026 mouse study found that long-term CoQ10 exposure reduced working-memory errors in Purkinje-cell-specific Drp1-deficient mice, tying the behavioral rescue to Coa6 binding and support fo…
Read articleA matched case-control study of 50 children with autism spectrum disorder and 50 controls found that newborn amino acid metabolism overlapped with both later autism diagnosis and prenatal ai…
Read articleA 2026 mechanistic review linked microplastics to 6 proposed Alzheimer’s disease pathways and 6 proposed Parkinson’s disease pathways.1 The calibrated interpretation is that microplastics ar…
Read articleA 2026 meta-analysis of 54 human studies found that 8-hydroxy-2′-deoxyguanosine rose in Parkinson’s disease, while F2-isoprostanes did not show a statistically confirmed Parkinson’s signal; …
Read articleA Nature Communications study found that old vertebrate brains lost almost 40% of cysteine protease deubiquitylase catalytic activity with age, despite relatively stable protein abundance.1 …
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