Movie Neurofeedback Lowered Opioid Craving More Than Sham
In a 20-person preprint study, live fMRI feedback while watching Trainspotting lowered movie-cue craving and improved mood in opioid use disorder more than sham feedback.
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Published research on orbitofrontal cortex.
bvFTD MRI Atrophy Ratings: Left Orbitofrontal Score Predicted 3.77x Odds
A 2026 behavioral-variant frontotemporal dementia MRI study found that simple visual ratings of orbitofrontal and frontoinsular brain atrophy helped separate probable from possible bvFTD, wi…
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Catatonia Brain Circuits: Limbic System Review
A 2026 systematic review argues that catatonia should be read as a limbic-cortical circuit syndrome, with motor shutdown tied to brain systems for threat, salience, motivation, and emotional…
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Right OFC rTMS Improves Memory in Early Schizophrenia
Cognitive impairment in first-episode schizophrenia (FES) is the symptom that does the most work blocking employment, relationships, and independent living — and the symptom current antipsyc…
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Prior Cocaine Use Disrupts Orbitofrontal Hidden-State Coding
A 2026 eLife study recorded 3,881 lateral orbitofrontal cortex units in rats and found that prior cocaine use made the OFC over-distinguish task positions that controls treated as functional…
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tDCS of the DLPFC Treats Anhedonia in Depression & Improves Social Functioning (2024 Study)
In the quest to find more effective treatments for depression, particularly the challenging symptom of anhedonia, Transcranial Direct Current Stimulation (tDCS) emerges as a promising option…
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Proton Pump Inhibitors (PPIs) May Treat OCD via Neuronal pH & Dopamine Modulation (2024 Study)
Obsessive-compulsive disorder (OCD), a prevalent neuropsychiatric condition, presents significant treatment challenges due to its varied symptom patterns and poor response to traditional med…
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