Ketamine and its S-enantiomer esketamine (sold as Spravato) are now established treatments for treatment-resistant depression and acute suicidality. The standard safety pitch from sponsors and clinics: at single sub-anesthetic doses, in supervised settings, addiction risk is minimal. A new case report in BJPsych Open documents a patient for whom that pitch failed catastrophically — and …
Magnesium is regarded as an essential mineral for humans and functions as a cofactor in upwards of 300 biochemical processes throughout the body. For example, magnesium is implicated in: ATP production, blood pressure regulation, bone development, glucose modulation, heart rhythm normalization, muscle and nerve function, plus protein synthesis. Knowing that magnesium is essential for optimal …
Namenda (Memantine) is a drug that was approved by the FDA in 2003 for the treatment of Alzheimer’s disease. Research suggests that Namenda has a small effect in reducing symptoms among those diagnosed with moderate or severe cases of Alzheimer’s. It appears to have no significant effect when administered to individuals diagnosed with milder cases …
Ketamine is a drug that is used to induce sedation in humans in a controlled environment. It is also used recreationally and is referred to as “Special K.” Ketamine is an NMDA antagonist that functions as a sedative, analgesic, and has therapeutic properties when used with an anesthetic. In regards to recreational usage, Ketamine has …
Lanicemine (AZD6765) is an NMDA antagonist developed by the company AstraZeneca in hopes to help people with treatment-resistant depression. Let’s face it, if you have treatment-resistant depression, you are probably waiting for some sort of breakthrough in technology and/or a new class of drugs for treatment. Although many people find benefit from SSRI’s, TCA’s, and …