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Mirapex (Pramipexole) For Depression: An Effective Antidepressant?

Mirapex (Pramipexole) is a drug that is approved by the FDA for the treatment of Parkinson’s disease and RLS (restless leg syndrome).  Classified as a dopamine receptor agonist, pramipexole elicits partial or full agonism upon D3 receptors, D2 receptors (2L/2S), and D4 receptors.  Interestingly, pramipexole also appears to modify mitochondrial function, and to a negligible …

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