Gabapentin is a drug that was approved by the FDA in 1993 as an adjunct treatment for epileptic seizures. It has since attained approval for the treatment of partial seizures in adults and children. In addition to its mechanism as an antiepileptic drug, Gabapentin functions as an analgesic, and was approved in 2004 for the …
Guanfacine is a drug that was developed primarily for the treatment of hypertension (high blood pressure). It has been proven as an effective medication to reduce both systolic and diastolic blood pressure via its effect on Alpha-2 adrenergic autoreceptors. It functions by stimulating these receptors (as an agonist) and reducing activation of the sympathetic nervous …
Methadone was originally developed in Germany during the 1930s as a synthetic alternative to opium. Post World War II, the United States obtained all research records for the substance and noted that it was less sedating and less of a respiratory depressant than morphine. In 1947, Methadone was approved by the FDA for the treatment …