MentalHealthDaily

How Long Does Nortriptyline Stay In Your System?

Nortriptyline (brand name “Pamelor”) is considered the chief pharmacologically active metabolite of the chemical amitriptyline, a tricyclic antidepressant derived from dibenzocycloheptene. Formation of nortriptyline occurs upon hepatic oxidative N-demethylation of amitriptyline via CYP2D6 and CYP2C19 isoenzymes. In the early 1960s, researchers realized a significant portion of amitriptyline’s antidepressant effects resulted from the formation of its …

How Long Does Amitriptyline Stay In Your System?

by GLOOM

Amitriptyline (brand name “Elavil”) is a drug derived from the chemical dibenzocycloheptadiene that was discovered and approved in the early 1960s for the treatment of major depression. It is formally classified as a tricyclic antidepressant (TCA) and functions principally via inhibiting the presynaptic reuptake of norepinephrine and serotonin. This effect of dual presynaptic reuptake inhibition …

How Long Does “DXM” Stay In Your System?

by GLOOM

DXM (Dextromethorphan) is an antitussive agent comprised solely of a methylated dextrorotatory analogue of levorphanol, a semisynthetic non-opioid morphine derivative. It is classified as a “morphinan” drug and is an active ingredient within many over-the-counter (OTC) formulations utilized to treat allergies, coughing, influenza, and more. Examples of several popular over-the-counter formulations with DXM as an …

How Long Does Promethazine Stay In Your System?

by GLOOM

Promethazine is a first-generation antihistamine of the “phenothiazine” classification often prescribed for the treatment of postoperative nausea, vomiting, and motion sickness. It is commonly utilized as an adjunct to narcotic analgesics to increase their efficacy among those experiencing acute or chronic pain. Additionally, promethazine is sometimes administered for the treatment of the common cold and …

How Long Does DayQuil Stay In Your System?

by GLOOM

DayQuil is an over-the-counter (OTC) medication sold by Procter & Gamble under the brand “Vicks.” It is manufactured in approximately 5 formulations, each of which contain a unique set of ingredients aimed to target a specific symptom (e.g. coughing) or multiple symptoms as one would experience with the common cold and/or influenza. DayQuil is considered …

How Long Does Lortab Stay In Your System?

by GLOOM

Lortab is a brand name medication engineered to contain active ingredients hydrocodone bitartrate (a synthetic opioid) and acetaminophen (a non-opioid analgesic). The drug is typically prescribed for the treatment of moderate to severe acute, chronic, or postoperative pain. The hydrocodone component of Lortab functions via binding to opioid receptors in the central nervous system, principally …

How Long Does Benadryl Stay In Your System?

by GLOOM

Benadryl is a brand name for a variety of over-the-counter (OTC) medications containing the chemical diphenhydramine, an antihistamine. The drug was initially synthesized in 1943, was acquired by Pfizer in 1946, and became the first antihistamine to receive FDA approval in the United States. The brand “Benadryl” was acquired by Johnson & Johnson (from Pfizer) …