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Antidepressants & Dementia Risk in Elderly Users: SSRIs vs. TCAs (2024 Study)

Recent research has uncovered connections between the use of antidepressants and the risk of developing dementia in the elderly. This complex relationship, marked by varying results and considerations, is becoming a critical area of study in geriatric medicine and mental health. In light of these findings, it is crucial to delve into the nuances of …

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Semaglutide & Empagliflozin May Treat Obesity-Related Cognitive Impairment (Mouse Study)

Obesity now affects over 650 million adults globally and is a major risk factor for various chronic diseases including cognitive decline and impairment. Recent evidence shows a link between obesity, reduced brain volume and neuronal loss, increased dementia risk, and impaired learning, memory and cognition. Preliminary evidence suggests that weight loss drugs like semaglutide may …

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Long COVID Brain Fog & Cognitive Deficits Linked to Specific Biomarkers

A large prospective study has uncovered two blood biomarker profiles measured during acute COVID-19 that are associated with cognitive deficits months later. Higher fibrinogen and lower C-reactive protein predict both objective and subjective cognitive impairment. Higher D-dimer and lower C-reactive protein predict subjective deficits and occupational impact. Key Facts: In 1,837 COVID-19 patients, two acute …

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Long Term Effects of Modafinil: Hypothetical Risks & Rewards

Modafinil (brand name “Provigil”) is a blockbuster eugeroic drug synthesized by Cephalon Pharmaceuticals (now Teva) and approved in 1998 for the treatment of excessive daytime sleepiness (EDS) associated with narcolepsy.  It was since approved for the treatment of excessive daytime sleepiness associated with obstructive sleep apnea, as well as to normalize circadian rhythms in diagnoses …

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Neurofeedback Side Effects, Adverse Reactions, & Dangers

Neurofeedback is a training technique that helps you learn how to consciously change the electrical activity (brain waves) in your brain.  All electrical oscillations influence your state of consciousness, arousal, and ability to function.  Neurofeedback is based on the idea that many individuals, particularly those with psychological conditions (e.g. ADHD) have suboptimal brain waves in …

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Insomnia Symptoms & Signs (List)

We’ve all had nights that we’ve gone to bed, closed our eyes, but no matter how much we relaxed or how many sheep we counted, we weren’t able to fall asleep.  An inability to fall asleep is medically referred to as “insomnia.”  Although an inability to fall asleep is a common manifestation of insomnia, sometimes …

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