A 2026 double-blind randomized controlled trial by Kappes et al. in Psychopharmacology found something the smart-drug users likely wouldn’t have predicted: a single 30 mg dose of methylphenidate reduced dishonest misreporting on a die-rolling task from ~22% of trials in the placebo arm to ~6% (in the methylphenidate arm).1 Atomoxetine, a noradrenergic comparator, had no …
An overwhelming majority of medications used to treat ADHD (attention-deficit/hyperactivity disorder) are classified as psychostimulants. Although psychostimulant drugs tend to have an immediate effect in reducing symptoms of attentional deficits and hyperactive behavior, they have a high potential for abuse. Furthermore, there is something to be said for the potential that long-term psychostimulant use may …
Strattera (Atomoxetine) is a relatively well-known NRI (norepinephrine reuptake inhibitor) that is commonly used for the treatment of ADHD. Its mechanism of action involves inhibiting the reuptake of the neurotransmitter norepinephrine, thereby increasing extracellular levels. This tends to result in a stimulating effect, which boosts overall cortical activity and helps improve cognitive function among those …
Norepinephrine Reuptake Inhibitors (NRIs) are drugs that function primarily by inhibiting the reuptake of the neurotransmitter norepinephrine (noradrenaline) and/or epinephrine (adrenaline). Inhibiting the reuptake of norepinephrine tends to elicit stimulating effects, thereby increasing both cortical arousal and energy levels. The NRI drugs are typically prescribed to individuals that may benefit from increased arousal such as …
Strattera is an NRI or “norepinephrine reuptake inhibitor” meaning it prevents the reuptake of the neurotransmitter norepinephrine. This drug has been found clinically effective for treating cases of ADHD. Many doctors prefer to prescribe this drug over a potent stimulant like Adderall simply because it doesn’t have any major addictive properties or potential for abuse. …
Strattera (Atomoxetine) is a unique drug that was created to treat ADHD (attention-deficit hyperactivity disorder). Unlike common stimulants, it works by inhibiting the reuptake of the neurotransmitter norepinephrine. It is important to understand that this is not the same as an SNRI medication that is used for depression. This is a drug that is considered …