Cannabis users often say the drug helps them blunt stressful memories. A 2026 randomized trial of 36 healthy adults tested low-dose oral THC against placebo during retrieval of a standardized lab stressor, and on every subjective and physiological measure that mattered, THC did nothing.1 Research Highlights 36-adult, 3-arm RCT: participants got placebo, 5 mg oral …
Inositol (cyclohexane-1,2,3,4,5,6-hexol) is a non-essential nutrient synthesized within the body from glucose and is abundant within spinal fluid. Although inositol exists in the form of 9 distinct stereoisomers, the most abundant format within cellular membranes is myo-inositol, accounting for approximately 95% of free inositol within the body. Myo-inositol was initially isolated by researchers in 1849, …
L-Theanine is a non-essential amino acid derived primarily from the plant Camellia sinensis. It was discovered as a green tea constituent circa 1950, and can also be found within other types of tea including black tea and white tea. The levorotatory “L” (left-handed) enantiomer is more popular than the dextrorotatory “D” enantiomer and better understood. …
In recent years, biotech and pharmaceutical companies have been developing new classes of antidepressants. These new classes attempt to improve on older classes of medication in regards to efficacy, side effects, and tolerability. One such class that is being developed is that which targets opioid receptors, particularly the kappa receptor. These drugs are classified as …