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Doxycycline Causes Depression, Anxiety, Suicidal Ideation?

Doxycycline is a broad-spectrum tetracycline antibiotic that kills bacteria and protozoa by inhibiting protein synthesis (aminoacyl-tRNA to the mRNA-ribosome complex).  The drug was patented in 1957, introduced as a pharmaceutical in 1967, and has received medical approval as a treatment for conditions such as: acne, bacterial pneumonia, chlamydia, cholera, Lyme disease, Rocky Mountain spotted fever, …

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Autism, Gut Bacteria, & Probiotics for Treatment: A Complex Puzzle

Autism is a neurodevelopmental disorder associated with poor social skills, deficits in verbal and non-verbal communication, and frequent engagement in repetitive behaviors.  On average, it affects boys more frequently (~5-fold) than girls and signs of the disorder become noticeable in early childhood [between ages 1 and 3].  Estimates suggest that over 21 million individuals throughout …

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Minocycline For Depression: Antibiotics As Antidepressants?

Minocycline is a broad-spectrum antibiotic of the tetracycline classification, indicating that its chemical structure consists of 4 hydrocarbon rings.  The fact that minocycline has a broad-spectrum mechanism indicates that it targets a wide-range of pathogenic (Gram-positive and Gram-negative) bacteria.  In fact, when compared to other tetracycline drugs, minocycline is regarded as having the “broadest spectrum” …

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