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How Long Does Lortab Stay In Your System?

Lortab is a brand name medication engineered to contain active ingredients hydrocodone bitartrate (a synthetic opioid) and acetaminophen (a non-opioid analgesic).  The drug is typically prescribed for the treatment of moderate to severe acute, chronic, or postoperative pain.  The hydrocodone component of Lortab functions via binding to opioid receptors in the central nervous system, principally …

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How Long Does Benadryl Stay In Your System?

Benadryl is a brand name for a variety of over-the-counter (OTC) medications containing the chemical diphenhydramine, an antihistamine.  The drug was initially synthesized in 1943, was acquired by Pfizer in 1946, and became the first antihistamine to receive FDA approval in the United States.  The brand “Benadryl” was acquired by Johnson & Johnson (from Pfizer) …

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How Long Does Chantix Stay In Your System?

Chantix (Varenicline) is a drug marketed by Pfizer for the treatment of nicotine addiction.  It functions as a selective, competitive partial agonist at α4β2 (alpha-4-beta-2) nAChRs.  Competitive partial agonism at the α4β2 receptors decreases the binding of nicotine to these receptors, thereby modulating the release of dopamine in the mesolimbic pathway as triggered by nicotine …

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How Long Does Fentanyl Stay In Your System?

Fentanyl is a synthetic opioid drug that was originally synthesized in the early 1960s by Paul Janssen, founder of Janssen Pharmaceutica.  The drug initially gained mainstream popularity as a general anesthetic in the 1960s under the brand “Sublimaze”, a compound consisting of fentanyl and citric acid.  It wasn’t until the 1990s that fentanyl was approved …

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How Long Does Paxil Stay In Your System After Stopping?

Paxil (Paroxetine) is an antidepressant manufactured by GlaxoSmithKline that hit the market in 1992.  It was originally approved by the FDA for the treatment of major depression in adults.  The drug has since received FDA approval to treat a variety of other psychiatric and medical conditions including: generalized anxiety disorder, hot flashes, panic disorder, PTSD, …

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How Long Does Valium Stay In Your System?

Valium (Diazepam) is a popular benzodiazepine medication prescribed for an array of conditions including: acute anxiety, alcohol withdrawal, insomnia, panic attacks, restless leg syndrome, and seizures.  Like other benzodiazepines, diazepam functions as a positive allosteric modulator (PAM) of GABAA receptors.  Rather than binding to the same (“A”) subunit of GABAA receptors as the neurotransmitter GABA …

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