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Internet Addiction Linked to 5-HT2A Receptor Polymorphism: Serotonin HTR2A Gene rs6313 (2024 Study)

In the digital age, Internet Addiction Disorder (IAD) emerges as a complex interplay of technology, psychology, and genetics. This intricate relationship underscores the need for a multidisciplinary approach to understanding and addressing IAD. A recent study analyzed the genetic underpinnings of internet addiction and discovered a strong link with the serotonin 2A receptor gene (HTR2A) …

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Non-Medical Fentanyl Use: Drug Addiction Insights (2024 Review)

Fentanyl, a synthetic opioid exponentially stronger than morphine, has transitioned from an unwanted contaminant in the illicit drug market to a sought-after substance among people who use drugs (PWUD). This shift underscores a critical change in drug use patterns, motivations, and the associated demographic and socioeconomic factors contributing to its rising preference. Highlights: Fentanyl’s Potency: …

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CNQX as a Potential Drug Addiction Treatment via AMPA & Kainate Receptors (Glutamate) (2023 Study)

The journey to overcome addiction is fraught with challenges, not least due to the limited options available for pharmacological intervention. In recent research, the focus has shifted toward understanding the role of glutamate, a key neurotransmitter in the brain, in the development and persistence of addictive behaviors. One compound, CNQX, which antagonizes certain glutamate receptors, …

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tDCS for the Treatment of Cravings in Drug Addiction (2023 Review)

Transcranial direct current stimulation (tDCS) emerges as a promising, noninvasive treatment for reducing cravings in substance addiction. This technique involves the use of scalp electrodes to modulate neural activity, influencing cravings associated with drug addiction or substance dependence. Despite its promise, further research is needed to standardize protocols and understand long-term efficacy. Highlights: tDCS significantly …

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Epigenetics & Nicotine Addiction: Effects on Genes & Potential Treatments (2023)

Nicotine addiction is not just a habit; it’s a complex interplay of molecular changes altering the brain’s function and structure. Recent research sheds light on how nicotine interacts with our genetic makeup, leading to persistent cravings and relapse. Highlights: Nicotine & Epigenetic Modification: Nicotine alters the way genes are expressed in the brain, affecting behavior …

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Fioricet “High”: Intoxication From Butalbital-Containing Agents

Fioricet is a medication approved by the FDA for the treatment of three specific types of headaches including: tension, muscle contraction, and post-dural puncture.  It contains a unique blend of a barbiturate (butalbital 50 mg), a pain reliever (acetaminophen 300 mg), and a stimulant (caffeine 40 mg); hence the reason it is sometimes abbreviated as Butal-Acet-Caff.  …

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How To Overcome Any Addiction

Addiction is defined as uncontrollably seeking out pleasure or reward, despite negative consequences. Many people consider addiction to be a “disease” or something that they’ll have to battle for the rest of their lives. While it is impossible to become addicted to something you never try, individuals with pleasure-seeking personalities, reward deficiency syndrome, and mood …

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