MentalHealthDaily

Pregabalin (Lyrica) vs. Gabapentin (Neurontin)

Lyrica (pregabalin) and Neurontin (gabapentin) are both classified as “gabapentinoids” (i.e. α2δ ligands). As gabapentinoids, Lyrica (pregabalin) and Neurontin (gabapentin) are chemical analogues of the inhibitory neurotransmitter GABA (gamma-aminobutyric acid) that interact with α2δ subunit-containing voltage-dependent calcium channels. Development of gabapentin (Neurontin) was initiated in the 1970s by chemists at the pharmaceutical company Parke-Davis – …

The Most Dangerous Psychiatric Drugs: Highest Risk Medications

by GLOOM

If you’re taking a psychiatric drug, you probably hope that you’re taking the one with the lowest overall risk. Sure you want the drug to be therapeutic and alleviate your symptoms, but you also don’t want to take a drug with a rapid tolerance onset, debilitating side effects, and crazy withdrawal symptoms. Many dangerous psychiatric …

Subutex vs. Suboxone: What’s the Difference?

by GLOOM

Subutex and Suboxone are drugs that were approved by the FDA in 2002 for the treatment of opioid dependence. Both drugs contain the active ingredient buprenorphine, a semisynthetic opioid that acts as primarily as a partial mu-opioid receptor agonist. Buprenorphine also acts as an antagonist at the kappa and delta opioid receptors. Buprenorphine’s mechanism of …

Methadone vs. Suboxone: Comparison

by GLOOM

Methadone was originally developed in Germany during the 1930s as a synthetic alternative to opium. Post World War II, the United States obtained all research records for the substance and noted that it was less sedating and less of a respiratory depressant than morphine. In 1947, Methadone was approved by the FDA for the treatment …

Adderall vs. Vyvanse Comparison: Similarities & Differences

by GLOOM

With the increasing number of ADHD diagnoses, many individuals are turning to pharmaceutical psychostimulant medications as a means to alleviate symptoms. Historically, one of the most popular and effective treatment options for the treatment of attention-deficit hyperactivity disorder is Adderall, a medication comprised of 75% dextroamphetamine salts and 25% levoamphetamine salts. Adderall’s popularity hasn’t waned …

Are Antidepressants Addictive? It’s Debatable.

by GLOOM

Addiction is defined as repeatedly engaging in a particular behavior or using a substance to experience pleasure, regardless of the consequences. Some believe that addiction can be a result of environmental experiences and/or various psychological conditions. When most people think of addiction, they think of gambling, illicit drugs (e.g. cocaine), alcohol, and sex. One reason …