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How Long Does Prednisone Stay In Your System After Stopping?

Prednisone is a common synthetic corticosteroid medication that was initially synthesized in 1955.  Upon ingestion of prednisone, it doesn’t elicit significant biological effects until converted via the liver to the pharmacologically active chemical “prednisolone.”  Prednisolone functions as an irreversible glucorticoid receptor agonist, binding to alpha glucorticoid receptors (AlphaGRs) and beta glucorticoid receptors (BetaGRs) within bodily tissues …

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How Long Does Ambien Stay In Your System?

Ambien (Zolpidem) is a popular medication prescribed for the treatment of insomnia.  It is classified as a “nonbenzodiazepine” due to the fact that it shares a similar mechanism of action with benzodiazepines, but differs in its chemical structure.  Ambien delivers its sedative, hypnotic (sleep-inducing) effects by modulating receptors of GABA (gamma-amino-butyric-acid). It specifically functions primarily …

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How Long Does Vyvanse Stay In Your System?

Vyvanse (Lisdexamfetamine) is a psychostimulant medication manufactured by Shire Pharmaceuticals for the treatment of ADHD (attention-deficit/hyperactivity disorder).  Many consider Vyvanse to be a “new and improved” successor of the drug Adderall.  Vyvanse contains the ingredient Lisdexamfetamine which is pharmacologically inactive until metabolized; hence being classified as a “prodrug.” The fact that Vyvanse is a prodrug …

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How Long Does Effexor Stay In Your System After Stopping It?

Effexor (Venlafaxine) is a SNRI (serotonin-norepinephrine reuptake inhibitor) medication prescribed primarily for the treatment of major depressive disorder.  It was initially introduced to the market by Wyeth in 1993 when it became the first dual-reuptake inhibitor to attain FDA approval for depression.  It differed from the SSRIs in that in addition to solely inhibiting reuptake …

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How Long Does Methadone Stay In Your System?

Methadone is a popular synthetic opioid utilized for the treatment of opioid dependence as a “replacement therapy.”  Individuals addicted to highly potent opioidergic agents (e.g. heroin) are often prescribed methadone as a transitory “replacement” drug.  Administration of methadone as a replacement over heroin is preferred because it is medically viewed as being slightly less addictive.  …

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How Long Does Ritalin Stay In Your System?

Ritalin is a psychostimulant drug used medically for the treatment of attention-deficit/hyperactivity disorder (ADHD) and narcolepsy.  It contains the active ingredient methylphenidate, which functions as a catecholamine reuptake inhibitor, primarily of dopamine (DAT) and norepinephrine (NET) transporters.  This reuptake inhibition (NDRI) facilitates increases in extracellular dopamine and norepinephrine concentrations, thereby substantially enhancing neurophysiological arousal. Upon …

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