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Women With Problematic Sexual Behavior Had Higher NSSI Risk

MHD featured image for non-suicidal self-injury and problematic sexual behavior.

A 2026 preprint combining 2,189 university participants with 477 clinical patients with problematic sexual behavior found a gender-specific self-harm signal: women with problematic sexual behavior had higher non-suicidal self-injury risk, but clinical severity of problematic sexual behavior did not predict NSSI inside the patient cohort.1 Research Highlights Total sample was 2,666 people: Jiang et al. …

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Anxiety Biomarkers: gp130, MMP-1, APRIL in 190 Adults

Stylized illustration of an anxious silhouette overlaid with vials and three biomarker labels (gp130, MMP-1, APRIL), representing the inflammation-anxiety biomarker associations in the Cancer Disparities Research Network cohort.

The link between psychological stress and chronic inflammation is well-documented — what’s been less clear is which specific inflammatory proteins move with anxiety in real-world community samples. A 2026 analysis from Loomans-Kropp et al. measured a 33-marker panel in 190 minoritized and medically underserved adults from the Cancer Disparities Research Network and identified three biomarkers …

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Teen Substance Use Prediction: Dynamic ABCD Models Improved AUROC

Editorial card showing adolescent substance-use risk pathways over time, with dynamic prediction outperforming baseline-only models.

A 2026 ABCD Study preprint found that teen substance-use initiation prediction improved more when models included changing risk over time than when they simply switched from logistic regression to multi-task learning.1 Dynamic models raised AUROC by 0.044 to 0.062 in multi-task learning and by 0.050 to 0.084 in logistic regression, which makes timing the main …

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New Psychoactive Stimulant Deaths in Australia: 70 Toxicology Cases

Australian coronial data show that fatal poisonings involving new psychoactive stimulants and hallucinogens were rarely single-drug events. In 70 toxicology-confirmed deaths from 2007 through 2025, 92.9% involved other psychoactive drugs and 75.7% involved multiple stimulants or hallucinogens. Research Highlights Fatal cases were usually polysubstance cases: 65 of 70 deaths (92.9%) had psychoactive drugs beyond the …

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