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CNQX as a Potential Drug Addiction Treatment via AMPA & Kainate Receptors (Glutamate) (2023 Study)

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The journey to overcome addiction is fraught with challenges, not least due to the limited options available for pharmacological intervention. In recent research, the focus has shifted toward understanding the role of glutamate, a key neurotransmitter in the brain, in the development and persistence of addictive behaviors. One compound, CNQX, which antagonizes certain glutamate receptors, …

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T2943 Treats Depression via Epigenetics: HDAC5 Inibitor in Hippocampus (2024 Study)

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Depression remains one of the most pervasive and challenging mental health conditions, affecting millions worldwide with a significant number not responding to traditional treatments. Emerging research underscores the role of histone modifications in depression, pointing towards epigenetic mechanisms as potential targets for novel antidepressants. Specifically, a compound known as T2943 (a histone deacetylase-5 (HDAC5) inhibitor), …

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Caffeine & Depression: Lower Risk with >90 mg per Day in Adults (2022 Study)

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In the quest to understand the intricate links between our dietary habits and mental health, a recent study leveraging data from the National Health and Nutrition Examination Survey (NHANES) 2017-2018 offers new insights into how caffeine consumption correlates with depression. This comprehensive analysis reveals that moderate caffeine intake might have a protective effect against depression, …

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Calorie Restriction (CR) Effects on Brain Gene Expression & Behavior in Rats (2023 Study)

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Calorie restriction (CR) is increasingly recognized for its potential benefits beyond just weight loss, including reducing anxiety, slowing aging, and mitigating the risk of obesity. Recent research focused on how both short-term and long-term CR affect behavior and gene expression in various brain regions, providing insights into the molecular underpinnings of these effects. Highlights: Behavioral …

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Effects of Coffee & Caffeine on Brain Connectivity in Habitual Drinkers (2023 Study)

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Coffee, one of the world’s most consumed beverages, is often lauded for its ability to enhance alertness and cognitive performance. Recent studies utilizing advanced neuroimaging techniques like resting-state functional magnetic resonance imaging (fMRI) have begun to unravel the intricate ways in which coffee, and its key component caffeine, modulate brain activity. This exploration into the …

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Cannabidiol (CBD): Neuropsychiatric Uses, Mechanisms, Effects on Brain (2023 Review)

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Cannabidiol (CBD), a compound found in Cannabis sativa, has emerged as a substance of interest in the medical community due to its potential therapeutic benefits for various neurological and mental disorders. This comprehensive review examines the current scientific understanding of CBD’s effects on brain function, its potential as a therapeutic agent, and the ethical and …

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Maternal Religiosity vs. Adolescent Mental Health: Atheist & Highly Religious Most Problematic (2024 Study)

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A study investigated the relationship between maternal religiosity and adolescent mental health, utilizing the data from the Avon Longitudinal Study of Parents and Children (ALSPAC). The study’s nuanced approach, including latent class analysis, sheds new light on how different forms of maternal religious belief are associated with various mental health outcomes in adolescents. It offers …

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