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Zembrin® (Sceletium tortuosum) for Anxiety & Depression: Testing Alkaloid-Specific Effects (2023 Study)

Sceletium tortuosum (ST) Extract, known as Zembrin®, is a traditional South African remedy was recently evaluated for its nuanced effects on anxiety and depression through a unique study using zebrafish larvae. Highlights: Zebrafish Larvae as Model Organisms: A study used zebrafish larvae to observe Zembrin®’s anxiolytic & antidepressant-like effects, offering a detailed and dynamic understanding …

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Caffeine’s Effects on Cerebral Blood Flow (CBF): What You Should Know

Caffeine, a ubiquitous stimulant, is known for its ability to enhance alertness and cognitive function. But beyond these surface-level effects lies a complex interaction with the body’s cardiovascular and neurological systems, particularly influencing cerebral blood flow. Highlights: Global Ubiquity: Caffeine is the most widely consumed pharmacologically active substance worldwide. Dose-Dependent Effects: Caffeine’s influence on cerebral …

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BPC-157 Peptide for Neurological & CNS Disorders: Preliminary Research

BPC 157, a stable gastric pentadecapeptide, has recently emerged as a promising therapeutic agent due to its multifaceted role in treating various central nervous system disorders. Its ability to mitigate conditions like stroke, schizophrenia, and spinal cord injuries while promoting neural recovery and functional improvement is capturing the interest of the medical community. Highlights: BPC …

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Antidepressants, Bacterial Mutations, & Antibiotic Resistance?

Antibiotics have long been the cornerstone of modern medicine, but their effectiveness is increasingly threatened by the rise of antibiotic resistance. While the overuse of antibiotics is a well-acknowledged culprit, recent research reveals a surprising and relatively unexplored contributor: antidepressants. Highlights: Antidepressants and Resistance: Antidepressants, particularly those used in large quantities like SSRIs and SNRIs, …

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Top Antidepressants to Quit Smoking: Bupropion & Nortriptyline (2023 Evidence Review)

In the ever-evolving fight against tobacco addiction, the potential of antidepressants, particularly bupropion and nortriptyline, as smoking cessation aids has come into sharp focus. A comprehensive review evaluated the efficacy, potential harms, and tolerability of these medications, providing insights into their role in helping smokers quit. Highlights: Bupropion significantly increases the chances of long-term smoking …

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Best Antidepressants for Preventing Depression Relapse & Maintenance Treatment (Study)

Depression is a complex, often long-term condition requiring careful management. Recent research has shed light on the effectiveness of various antidepressants during the maintenance phase of major depressive disorder (MDD). Highlights: Extensive Study: The meta-analysis included 34 double-blind, placebo-controlled trials with a total of 9,384 participants. Multiple Drugs Analyzed: 20 different antidepressants were compared for …

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Antidepressants May Trigger Mania In Bipolar Disorder via Mitochondria

Antidepressants, commonly used to treat major depressive episodes in bipolar disorder, might have more profound effects on our body’s energy factories, the mitochondria, than previously understood. A recent study examined how certain antidepressants alter mitochondrial energetics, potentially influencing the risk of treatment-emergent mania in bipolar disorder patients. Highlights: Antidepressants Double Edged Sword: While crucial for …

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