Mental Health DailyResearch. Evidence. Perspective.Published research on Drugs.
Statins do not look like a dementia-prevention drug, but they do not look like a dementia hazard either. In 322,358 Kaiser Permanente Northern California patients followed for an average of …
Read articleA 12-week randomized pilot trial in 60 Veterans with depression and psychiatric polypharmacy found that 30% had an actionable antidepressant gene-drug interaction, but immediate access to ph…
Read articleThe endogenous opioid system has been a candidate target for novel anxiety treatments, but a 2026 placebo-controlled crossover fMRI study in 38 healthy volunteers ran opposite the hypothesis…
Read articleIntranasal esketamine — FDA-approved for treatment-resistant depression in 2019 — failed cost-effectiveness benchmarks against four cheaper third-line options in a 2026 Hong Kong modeling st…
Read articleA 2026 methylome-wide association study by Shen et al. found 48 CpG methylation sites tied to the quadratic CYP2C19 metabolizer-status term in 18,396 Generation Scotland participants, with 1…
Read articleA 2026 study of 958 adults entering Japanese multidisciplinary pain centers found that 17.1% screened positive for ADHD, rising to 27.4% among patients whose average pain was NRS 9-10; ASD s…
Read articleA 2026 PPMI analysis found that Parkinson’s patients with positive CSF α-synuclein seed amplification assay results kept gaining levodopa benefit over follow-up, while SAA-negative patients …
Read article
