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2 New Kappa Opioid Receptor (KOR) Antagonists For Depression

The quest to come up with a superior antidepressant is in full effect among biotech and pharmaceutical companies. Although there are some companies that are still tweaking various formulations of serotonergic, noradrenergic, and dopaminergic substances (e.g. triple reuptake inhibitors) others are thinking outside the box. Based on current trends, the next decade or two of …

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New Antidepressant GLYX-13 (Clinical Trials): Partial NMDA Receptor Agonist

A new antidepressant chemically named “GLYX-13” was developed by the biotech company Naurex for individuals with treatment-resistant depression. It is currently in clinical trials as an antidepressant augmentation strategy, meaning it is used as an add-on to already approved treatments. However, most evidence would suggest that it works extremely well as a standalone treatment option. …

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How To Improve Psychiatric Treatment Outcomes with Technology & Variable Tracking

It’s blatantly obvious that psychiatry is an imperfect practice. These days people often seek the help of a psychiatrist with the belief that a pill can be prescribed to essentially cure a disease or get symptoms of a mental illness under control. While psychiatry can offer many benefits in the treatment of certain conditions, especially …

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Antidepressant Roulette: Switching / Trying New Medications Is Often Problematic

Many people seek out treatment for their depression from general practitioners and psychiatrists. If you have a serious mental illness that requires pharmaceutical treatment, it is generally best to work with a quality psychiatrist. Regardless of whether you seek the help of a psychiatrist or simply go to your family doctor, finding the right antidepressant …

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Why Antidepressants Stop Working + Solutions

Many people are taking antidepressants to treat major depression or one of the many other conditions (i.e. anxiety, PTSD, OCD) for which they are prescribed. Antidepressants are clinically effective based on scientific research, which is why they are accepted as being first-line treatment options for depression. For certain people, taking antidepressants have improved their life …

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