A 2026 analysis of 41 randomized studies involving 21,025 adults with schizophrenia found the largest estimated reductions in hostility and aggression for clozapine (standardized mean difference, or SMD, of −0.75), paliperidone (−0.62), and olanzapine (−0.60) vs. placebo.1 Confidence in every comparison was low or very low, the top 3 were not statistically separable, and most …
Trans people in Europe reported more discrimination and violence than cisgender lesbian, gay, and bisexual people in a 30-country survey of 138,212 respondents. The gap concentrated in identity-based discrimination, physical or sexual attacks, disability, ethnic-minority status, and gender identity within trans groups.1 Research Highlights 30-country gap was large and consistent: trans respondents reported discrimination in …
Paranoid schizophrenia is one of the 5 main subtypes of schizophrenia characterized by an intense paranoia which is often accompanied by delusions and hallucinations. Most people with paranoid schizophrenia have auditory hallucinations (i.e. they hear voices) and may experience delusions that people are “plotting” against them. For example, someone with this illness may believe that …