Provigil (Modafinil) is a eugeroic drug that was originally approved in 1998 for the treatment of excessive daytime sleepiness associated with narcolepsy, shift work sleep disorder, and obstructive sleep apnea. Despite never attaining FDA approval for the treatment of depression, many anecdotal reports highlight the efficacy of Provigil as an antidepressant. The drug tends to …
A new antidepressant chemically named “GLYX-13” was developed by the biotech company Naurex for individuals with treatment-resistant depression. It is currently in clinical trials as an antidepressant augmentation strategy, meaning it is used as an add-on to already approved treatments. However, most evidence would suggest that it works extremely well as a standalone treatment option. …
ALKS-5461 is a new drug that is being developed by the company Alkermes as an alternative to SSRI’s for the treatment of depression. ALKS-5461 (its trial name) is a combination of both buprenorphine (suboxone) and samidorphan, and is regarded as a non-addictive opioid modulator and antidepressant. It is currently being developed specifically as an antidepressant …
As technology advances, it is hoped that newer, more effective treatments for mental illness are developed. One newer treatment option that has been tested is that of Low-Field Magnetic Stimulation (LFMS). It has been found that low-field magnetic stimulation is capable to provide both immediate and significant improvement in mood with zero reported side effects. …
I’m not sure when pharmaceutical companies started marketing that a “chemical imbalance” is the cause of depression. Either way, this is a great marketing ploy that really gets people to believe that if they are feeling “depressed,” it must be a result of a natural chemical imbalance. In reality, most people do not likely have …
Antidepressant augmentation strategies are commonly reviewed when an individual is unresponsive to monotherapeutic treatment. In other words, people that try treatments by themselves such as: using an SSRI medication or going to cognitive behavioral therapy (CBT) may not have as great of a response as if the treatments were combined. In some cases, a person …
Suboxone (Buprenorphine) is a medication that is used by people withdrawing from narcotics (opioids). It helps alleviate withdrawal symptoms and most people end up able to experience a smooth withdrawal while on this particular drug. In people that have either extreme or treatment-resistant depression, many have turned to trying a variety of drugs besides that …