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TSPO Ligands For Anxiety: Targeting the Peripheral Benzodiazepine Receptor

Just recently researchers were able to unveil the crystallized structure of translocator protein. It has long been thought that various polymorphisms of the TSPO gene create dysfunctional variations of the translocator protein (18 kDa). The 18 kDa translocator protein is hypothesized to contribute to certain mental illnesses, particularly anxiety disorders. The newly discovered crystallized structure …

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Translocator Protein (TSPO) Structure To Spur New Treatments For Anxiety

Michigan State University (MSU) researchers recently published new data in the journal “Science” providing a first ever look at the crystallized structure of translocator protein (TSPO) (18kDa). Translocator protein is located within the outer portion of the mitochondrial membrane. Its primary¬†function is to transport cholesterol within mitochondria, which then is utilized to produce steroids. TSPO …

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