transcranial direct current stimulation Archives

Non-Invasive Prehabilitation Shifted Brain Tumor Language Networks

by GLOOM

MHD featured image for non-invasive prehabilitation, brain tumors, and language-network plasticity.

A 2026 brain tumor prehabilitation study involving 26 surgical patients found that language-targeted non-invasive stimulation plus intensive language training shifted fMRI language activation away from the stimulation target, while measured language and cognition stayed stable. Research Highlights Language-targeted prehabilitation moved the fMRI signal: the group-by-time interaction for stimulation-target overlap was significant, F(1,23) = 4.61, p …

Single-Session tDCS Fails Working-Memory Test in Schizophrenia

by GLOOM

Stylized illustration of tDCS electrodes positioned over the right dorsolateral prefrontal cortex on a brain outline, with a pre-post working-memory task in the foreground, representing the null-result trial in schizophrenia.

Transcranial direct current stimulation (tDCS) has been pitched as a scalable cognitive-enhancement tool for schizophrenia, where roughly 98% of patients show working-memory deficits, but a 2026 sham-controlled crossover trial from Ke et al. delivered the standard 1.5 mA anodal protocol over the right DLPFC to 27 stable patients and found no detectable benefit over sham.1 …

At-Home tDCS Trial (HomeDC) Prematurely Terminated Due to Skin Lesions & Safety Concerns (2023 Study)

by GLOOM

Transcranial Direct Current Stimulation (tDCS) is emerging as a promising home-based treatment for Major Depressive Disorder (MDD), offering a non-invasive, cost-effective, and scalable option for patients. This treatment modulates cortical excitability, potentially altering neuronal activity in the brain areas associated with depression. However, a recent randomized controlled trial (RCT), the HomeDC trial, aimed at investigating …

Cognitive Function Does Not Predict Response to tDCS for Depression (2023 Trial)

by GLOOM

Transcranial Direct Current Stimulation (tDCS) has been explored as a potential treatment for major depressive disorder (MDD), particularly for patients who have not responded to traditional treatments like selective serotonin reuptake inhibitors (SSRIs). This non-invasive technique involves applying a weak electrical current to the prefrontal cortex of the brain, aiming to modulate neurocognitive functions. However, …

tDCS for Fibromyalgia: Efficacy of Transcranial Direct Current Stimulation (2024 Review)

by GLOOM

A recent systematic review and meta-analysis aimed to update the understanding of the efficacy and safety of transcranial direct current stimulation (tDCS) for treating fibromyalgia (FM), focusing on its effects on analgesia, antidepressant outcomes, and the reduction of FM’s impact. Highlights: Efficacy of tDCS: The analysis revealed that tDCS is effective in reducing pain intensity, …

tDCS for Insomnia & Sleep Disturbances: Targeting the Infralimbic Cortex to Ventrolateral Preoptic Area Pathway (2024 Study)

by GLOOM

In the quest to effectively treat insomnia, a condition plaguing millions worldwide, scientists are exploring innovative treatments beyond traditional medication. Transcranial Direct Current Stimulation (tDCS) emerges as a promising intervention, offering a non-invasive method to modulate brain activity and enhance sleep quality. A recent study suggests tDCS may treat stress-related sleep disturbances and highlights the …

tDCS of the DLPFC Treats Anhedonia in Depression & Improves Social Functioning (2024 Study)

by GLOOM

In the quest to find more effective treatments for depression, particularly the challenging symptom of anhedonia, Transcranial Direct Current Stimulation (tDCS) emerges as a promising option. This non-invasive brain stimulation technique targets specific brain regions to modulate activity and potentially alleviate symptoms. A recent study has shed light on the efficacy and safety of targeting …