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At-Home tDCS Trial (HomeDC) Prematurely Terminated Due to Skin Lesions & Safety Concerns (2023 Study)

Transcranial Direct Current Stimulation (tDCS) is emerging as a promising home-based treatment for Major Depressive Disorder (MDD), offering a non-invasive, cost-effective, and scalable option for patients. This treatment modulates cortical excitability, potentially altering neuronal activity in the brain areas associated with depression. However, a recent randomized controlled trial (RCT), the HomeDC trial, aimed at investigating …

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Brain Gene Editing with CRISPR-Cas9 RNPs as Non-Viral Vector Alternative in Mice (2023 Study)

CRISPR-Cas9 technology, a powerful tool for gene editing, has made significant strides in therapeutic applications, especially within the central nervous system (CNS). A recent study highlights the potential of non-viral delivery of CRISPR-Cas9 ribonucleoproteins (RNPs) into the mouse striatum, offering a promising alternative to viral vector-based delivery. Highlights: Non-Viral Delivery of CRISPR-Cas9: The study focuses …

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Morus Alba (White Mulberry): Medical Uses, Health Effects, Mechanisms (2023 Research)

Morus alba, a member of the Moraceae family, is not only known for its role in sericulture but also for its therapeutic potential. The plant’s traditional uses are backed by scientific research, indicating its effectiveness in various medical conditions. Highlights: Morus alba is utilized in traditional medicine for its analgesic, antibacterial, antidiabetic, and anti-inflammatory properties. …

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Potential Dangers Of Nootropics: What To Consider Before Using Smart Drugs

Nootropics or “smart drugs” tend to improve cognitive function to help people perform better, maximize productivity, and ultimately achieve their full potential. Most nootropics are regarded as safe and in some cases serve as “neuroprotective agents,” meaning they preserve brain function and cognition. There is even some evidence to suggest that they may help prevent …

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