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Dexamethasone Disrupts Mouse Sleep Through Orexin Hyperarousal

Photoreal illustration of a steroid pill bottle with overlay of disrupted sleep architecture, conveying glucocorticoid-induced insomnia mechanism.

A 2026 male-mouse study found that 30 mg/kg dexamethasone for 5 days increased light-phase wakefulness (t13 = 4.122, p = 0.0012), decreased NREM sleep (t13 = 4.412, p = 0.0007), and amplified orexin-neuron activity during NREM-to-wake transitions (F1,9 = 6.941, p = 0.0272). The result points to orexin-linked hyperarousal as a testable explanation for steroid-induced …

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7 Ways To Increase Your Cognitive Flexibility

Cognitive flexibility refers to the ability to transition thoughts between multiple concepts or perspectives.  It also refers to the ability to process multiple concepts simultaneously such as the color and shape of an object or perspectives of republicans and democrats.  An individual who is able to switch quickly from thinking about one concept, characteristic, or …

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How To Stop Nightmares & Bad Dreams

Nearly everyone has experienced what it’s like to wake up in the middle of the night from a bad dream or nightmare. For most people, experiencing a nightmare is considered relatively rare and an uncommon occurrence. Although an occasional nightmare may cause some feelings of discomfort, it isn’t generally a cause for concern. However, for …

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