Mental Health DailyResearch. Evidence. Perspective.Published research on polygenic risk score.
A 2026 German-Austrian cohort analysis found that people with schizophrenia who were taking quetiapine scored modestly higher on demanding working-memory tests than sex- and age-matched pati…
Read articleA 244-person functional MRI study found no significant evidence that ventral striatum activation during reward anticipation works as an endophenotype — a measurable trait used to connect inh…
Read articleA 2026 study by Bai et al. in Dialogues in Clinical Neuroscience uses Mendelian randomization (MR) — inherited genetic variants as a natural experiment to test causality — and concludes that…
Read articleA 2026 PRONIA preprint involving 727 discovery-sample participants found that early mental illness severity cut across psychosis risk, recent psychosis, and recent depression: groups with hi…
Read articleA 2026 multi-ancestry genome-wide association study of urinary aMT6s, a melatonin metabolite used as a proxy for overnight melatonin secretion, found 0 genome-wide significant loci in 11,744…
Read articleThe intricate connection between mental health and educational attainment is a subject of growing interest and importance. Recent studies have shed light on how genetic predispositions to ce…
Read articleA recent study examined how our genetic makeup influences our temperament traits, particularly in relation to depression. By analyzing the polygenic risk for depression (PRS) and its correla…
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