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Residual Sleepiness in Treated Sleep Apnea Linked to Memory Deficits

Stylized sleep-apnea treatment scene with CPAP, daytime sleepiness testing, and memory-task circuitry, representing cognitive deficits linked to residual sleepiness despite PAP adherence.

Some sleep apnea patients stay sleepy even when their CPAP is used 6+ hours a night and apnea events have been driven back to normal range. A 2026 cross-sectional study of 65 PAP-adherent adults found those residually sleepy patients performed measurably worse on global cognition, memory, executive function, attention, and processing speed than their well-rested …

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Smoking Linked to 1.75x Higher Sleep Apnea Severity in Pomerania Study

MHD featured image for smoking history and obstructive sleep apnea severity in a population polysomnography study.

A 2026 population-based polysomnography study involving 1,206 adults found current smokers had 1.75x higher odds of worse obstructive sleep apnea severity than non-smokers or occasional smokers after adjustment for age and body mass index. Former smokers showed almost the same overall signal — 1.76x higher odds than never smokers — but that part of the …

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Genetics of Major Depression Linked to Increased Risk of Obstructive Sleep Apnea (OSA) (2024 Study)

In a new study leveraging Mendelian Randomization, researchers highlight the complex interplay between psychiatric disorders, specifically major depressive disorder (MDD), and obstructive sleep apnea (OSA). This meticulous investigation sheds light on the genetic predispositions that suggest a causal relationship between MDD and increased risk of developing OSA, offering new insights into the bidirectional interconnections of …

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