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Oxycodone vs. Other Opioids: Distinct Epigenetic Effects & Molecular Adaptations (2023 Review)

The opioid crisis, particularly in North America, has spotlighted oxycodone as a central figure due to its significant role in addiction and overdose deaths. A recent review analyzed the genomic and epigenetic mechanisms behind oxycodone’s effects compared to other opioids, shedding light on its unique impact on addiction pathways. Highlights: Oxycodone, a semi-synthetic opioid derived …

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tDCS for the Treatment of Cravings in Drug Addiction (2023 Review)

Transcranial direct current stimulation (tDCS) emerges as a promising, noninvasive treatment for reducing cravings in substance addiction. This technique involves the use of scalp electrodes to modulate neural activity, influencing cravings associated with drug addiction or substance dependence. Despite its promise, further research is needed to standardize protocols and understand long-term efficacy. Highlights: tDCS significantly …

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Post Acute Withdrawal Syndrome: Causes, Symptoms, Treatment

Individuals that have used any potent drug, particularly for a long-term and/or at high doses are known to experience significant short-term withdrawal symptoms.  These symptoms may include things like dizziness, headaches, nausea, and vomiting.  Over time, they usually lessen in severity as the nervous system and physiology adjusts to function without the presence of the …

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