Opioid Use Disorder Brain Study Flags 18 Candidate Gene Variants
Postmortem nucleus accumbens tissue from 20 people with opioid use disorder showed 18 candidate variants needing DNA checks and 145 genes more active, led by immune genes.
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Published research on opioids.
6 Medicine Groups Linked to Fatal Overdoses in Bipolar Disorder
In a Finnish registry study, recent prescriptions for 6 medicine groups were linked to higher odds of fatal poisoning in bipolar disorder. Lithium was not.
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U.S. Substance-Use Disorder DALYs Rose 213.5%: Opioids Led
A Global Burden of Disease analysis estimated that U.S. age-standardized substance-use disorder disability-adjusted life-year rates rose 213.5% from 1990 to 2019, with opioid use disorders p…
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Fibromyalgia Costs in Saudi Arabia: $2,560 Annual Direct Medical Cost
A 2026 Saudi tertiary-hospital study estimated that adults treated for fibromyalgia — chronic widespread pain with fatigue, sleep disruption, cognitive symptoms, and overlapping mood or medi…
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Oxycodone vs. Other Opioids: Distinct Epigenetic Effects & Molecular Adaptations (2023 Review)
The opioid crisis, particularly in North America, has spotlighted oxycodone as a central figure due to its significant role in addiction and overdose deaths. A recent review analyzed the gen…
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tDCS for the Treatment of Cravings in Drug Addiction (2023 Review)
Transcranial direct current stimulation (tDCS) emerges as a promising, noninvasive treatment for reducing cravings in substance addiction. This technique involves the use of scalp electrodes…
Read articlePost Acute Withdrawal Syndrome: Causes, Symptoms, Treatment
Individuals that have used any potent drug, particularly for a long-term and/or at high doses are known to experience significant short-term withdrawal symptoms. These symptoms may include t…
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