nicotine replacement therapy Archives

Addiction Medications in 371 Trials: No Approved Medication for Stimulant Use Disorder

by GLOOM

MHD card showing a medication blister pack: the strongest addiction-medication evidence is for smoking and opioids; no medication is approved for stimulant use disorder.

A 2026 umbrella review of 16 systematic reviews covering 371 trials found strong medication evidence for tobacco and opioid use disorders, modest benefits for alcohol use disorder, and no approved drugs for stimulant or cannabis use disorders.1 Varenicline more than doubled smoking quit rates vs. placebo, methadone kept people in opioid treatment longer than buprenorphine, …

Optimizing Nicotine Replacement Therapy (NRT) to Quit Smoking (2023 Evidence)

by GLOOM

Nicotine Replacement Therapy (NRT) is a critical tool in the fight against smoking addiction, offering a beacon of hope for millions looking to quit. Recent studies have delved deep into the nuances of NRT, providing invaluable insights into its effectiveness, safety, and application. Highlights: Combination NRT has been found to be more effective than single-form …