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At-Home tDCS Trial (HomeDC) Prematurely Terminated Due to Skin Lesions & Safety Concerns (2023 Study)

Transcranial Direct Current Stimulation (tDCS) is emerging as a promising home-based treatment for Major Depressive Disorder (MDD), offering a non-invasive, cost-effective, and scalable option for patients. This treatment modulates cortical excitability, potentially altering neuronal activity in the brain areas associated with depression. However, a recent randomized controlled trial (RCT), the HomeDC trial, aimed at investigating …

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Deep Brain Stimulation (DBS) of Nucleus Accumbens (NAc) for Treatment-Resistant Depression (4 Case Reports)

Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD) explores the cutting-edge intersection of technology and neuroscience, offering hope to those for whom traditional treatments have failed. By targeting specific brain areas, such as the nucleus accumbens, DBS attempts to modulate the underlying neural circuits associated with depression. A recent review analyzed case reports documenting significant …

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Cognitive Function Does Not Predict Response to tDCS for Depression (2023 Trial)

Transcranial Direct Current Stimulation (tDCS) has been explored as a potential treatment for major depressive disorder (MDD), particularly for patients who have not responded to traditional treatments like selective serotonin reuptake inhibitors (SSRIs). This non-invasive technique involves applying a weak electrical current to the prefrontal cortex of the brain, aiming to modulate neurocognitive functions. However, …

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tDCS for Fibromyalgia: Efficacy of Transcranial Direct Current Stimulation (2024 Review)

A recent systematic review and meta-analysis aimed to update the understanding of the efficacy and safety of transcranial direct current stimulation (tDCS) for treating fibromyalgia (FM), focusing on its effects on analgesia, antidepressant outcomes, and the reduction of FM’s impact. Highlights: Efficacy of tDCS: The analysis revealed that tDCS is effective in reducing pain intensity, …

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Accelerated TMS for Depression: Is aTMS More Effective than Standard TMS? (2024 Review)

Depression, a common yet severe mood disorder, affects millions worldwide, posing significant challenges in both diagnosis and treatment. Recent advancements have led to the development of accelerated transcranial magnetic stimulation (aTMS), a novel approach aiming to offer rapid relief for individuals suffering from major depressive disorder (MDD). This revolutionary technique has shown promising results, potentially …

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tDCS of the DLPFC Treats Anhedonia in Depression & Improves Social Functioning (2024 Study)

In the quest to find more effective treatments for depression, particularly the challenging symptom of anhedonia, Transcranial Direct Current Stimulation (tDCS) emerges as a promising option. This non-invasive brain stimulation technique targets specific brain regions to modulate activity and potentially alleviate symptoms. A recent study has shed light on the efficacy and safety of targeting …

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Customized Transcranial Magnetic Stimulation (TMS) Protocols for Depression & Psychiatric Disorders Based on Personalized Neuroimaging (2023 Evidence)

Recent advancements in neuroimaging and brain stimulation techniques, particularly Transcranial Magnetic Stimulation (TMS), are revolutionizing the treatment of psychiatric disorders. These technologies, leveraging our understanding of individual brain network architectures, offer the potential for highly personalized treatments. Highlights: Personalization of Treatment: Neuroimaging advancements allow for the personalization of brain stimulation targets, particularly in Transcranial Magnetic …

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